High performance liquid chromatography: principles and clinical applications.

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High performance liquid chromatography: principles and clinical applications.

Detection of disease often relies on identifying abnormal molecules or imbalanced ratios of normal molecules in body fluids, these being reflections of abnormal metabolism. The study of these molecules and their interactions in both healthy and diseased states aids diagnosis and the monitoring of treatment. To carry out such investigations we need to identify, quantify, and ultimately purify th...

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High-Performance Liquid Chromatography Determination of Methotrexate in Plasma

This article describes a simple and fast high-performance liquid chromatography method for the determination of methotrexate (MTX) in plasma. Samples were collocted from children receiving high-dose MTX at shafa Hospital (Ahvaz University of Medical sciences, Ahvaz, iran) at various times after the end of eachinfusion. Plasma was deproteinized with trichloroacetic acid and the supernatant was i...

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High Performance Liquid Chromatography Determination of Sertraline in Human

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ژورنال

عنوان ژورنال: BMJ

سال: 1989

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.299.6702.783